Genetic Changes in Rat Brains Found with Persistent Exposure to Air Pollution

Genetic Changes in Rat Brains Found with Persistent Exposure to Air Pollution

A Cedars-Sinai study has found the presence of cancer-related genes and inflammation triggered in the brains of rats due to extended exposure to air pollution particles in the Los Angeles Basin. The medical center’s Nanomedicine Research Center director, Julia Ljubimova, MD, PhD pointed out the role of nickel or certain other coarse air pollution materials in genetic changes associated with disease development. The study actually found markers that indicated their role. Published in Scientific Reports on April 9, 2018, it took into consideration novel data collected in the Los Angeles area. It contains important implications for assessing air quality in the region.

Findings may be Unique to Composition of Air Pollution in Los Angeles Basin

There could be two ways that may have helped coarse particulate matter in air pollution to enter bodily systems, according to the study. The first one may be through the nose, where air pollution materials could be more directly absorbed into the brain. The other way may be through the lungs, where trace materials could make their way to the brain via the bloodstream. South Coast Air Quality Management District chair, William A. Burke, EdD said that his team is happy to support the research, and it has been an arduous and a long task to clean the air in Los Angeles Basin.

The trend of increased exposure to air pollution and urbanization in our modern society calls for a combined effort to focus on reduction in ambient air pollution levels and further research on the biology of organ damage induced by air pollution.

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