Lipid Accumulation in Brain Could Hint Parkinson’s Disease

Lipid Accumulation in Brain Could Hint Parkinson’s Disease

Researchers at the McLean Hospital, and Oxford University have found that early sign of Parkinson’s disease can be detected through elevated levels of lipids in the brain. This finding is extremely important for those people who might be at the risk of developing Parkinson’s disease and can allow for early treatment of the disease and might even prevent the person from getting Parkinson’s disease.

Parkinson’s disease is characterized by the production in the nerve cells especially dopamine neurons which are responsible for movement in the brain area. The loss of these nerve cells have been linked with toxic accumulation of the protein alpha-synuclein. Researchers have been studying link between a group of disorders as well as Parkinson’s disease which is caused by mutations which lead to loss of GBA Gene. This Gene produces an enzyme which breaks down lipids. Lipid accumulation can be important for Parkinson’s Disease.

The researchers have found that lipid alteration can be a cause of problems inside the nerve cells responsible for Parkinson’s Disease or degenerative aging. According to the researchers, protein aggregation is the hallmark of Parkinson’s disease. The analyzing of lipids early on can help treat the nerve cells from dying and treat Parkinson’s disease at an earlier stage

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