At present, over 80 nanotechnologies have received approval for different kinds of medical applications, ranging from treating cancer to tissue remodeling to bioimaging. Latest research show that nanoparticles containing enzyme can conduct small dental surgeries too. They can better the effect of dental braces meant to reorient drastically misaligned teeth back to their appropriate position.

They Work by Acting as Surgical Blades

In the tests conducted by the team of researchers, it was found that rats which were treated with the nanoparticles prior to being fitted with braces showed more efficient alignment of the tooth. They also had lesser chances of a relapse in tooth positions, quicker recovery, and much reduced pain in comparison to those rats on which traditional surgery was performed.

All the findings from the research was published recently. The team that conducted the tests was spearheaded by Avi Schroeder at Technion-Israel Institue of Technology.

As per Schroeder, enzymes help to overcome the biggest challenge posed by the currently used scalpel – inability to distinguish between diseased and healthy tissue. Proteolytic enzymes can do that and damage particular tissues, without harming the healthy ones. This is where their USP lies.

The new method was designed by researchers to tackle extreme misalignment of teeth, known as “malocclusion.” At present, the condition is treated with minor but painful surgery to sever the collagen fibers connecting the teeth to the bone. Braces are then fitted move the teeth into correct position. They dramatically bring down pain.

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